Opioids are naturally occurring opioids, such as heroin, morphine, and codeine. In general, prescribed opioid pain relievers are safe when taken for a short time as directed by your doctor. However, they are being abused by users because of the euphoria that comes with pain relief. As a result, substance abuse occurs when drugs are taken differently or in higher doses than prescribed, or when they are taken without a doctor’s prescription. Substance abuse with this drug is best treated accordingly as part of an inpatient program dedicated to treating opioid dependence.